Aim.To compare the diagnostic performance of diffusion weighted imaging (DWI) using b-values of 1000 Antifungal s/mm2 and 2000 s/mm2 at 3 Tesla (T) for the evaluation of clinically significant prostate cancer.Matherials and Methods.Seventy-eight prostate cancer patients underwent a 3T MRI scan followed by radical prostatectomy.DWI was performed using b-values of 0, 1000, and 2000 s/mm2 and qualitatively analysed by two radiologists.
ADC maps were obtained at b-values of 1000 and 2000 s/mm2 and quantitatively analyzed in consensus.Results.For diagnosis of 78 prostate cancers the accuracy of DWI for the young reader was significantly greater at b = 2000 s/mm2 for the peripheral zone (PZ) but not for the transitional zone (TZ).For the experienced reader, DWI did not show significant differences in accuracy between b-values of 1000 and 2000 s/mm2.The quantitative analysis in the PZ and TZ was substantially superimposable between the two b-values, albeit with a higher accuracy with a b-value of 2000 s/mm2.
Conclusions.With a b-value of 2000 s/mm2 at 3T both readers differentiated clinical significant cancer from benign tissue; higher b-values can be helpful Foggers for the less experienced readers.